LC
Lung Cancer Portal
HomeGWASAbout
Home
Geneprotein coding

KRAS

KRAS proto-oncogene, GTPase

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer ...

Aliases:KRAS1, K-Ras4B, KRAS2
Locationchr12:25,205,246-25,250,936
Strand-
Biotypeprotein coding
LOEUF0.559
pLI0.928
HGNCHGNC:6407UniProtP01116NCBI Gene3845OMIM190070

Relationships

No data available for this relationship type.