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Geneprotein coding

EGFR

epidermal growth factor receptor

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, e...

Aliases:ERBB1, ERRP, ERBB
Locationchr7:55,018,820-55,211,628
Strand+
Biotypeprotein coding
LOEUF0.475
pLI0.981
HGNCHGNC:3236UniProtP00533NCBI Gene1956OMIM131550

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