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Geneprotein coding

PRKN

parkin RBR E3 ubiquitin protein ligase

Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPT5, TOMM20, USP30, ZNF746 and AIMP2 (PubMed:10973942, PubMed:10888878, PubMed:1...

Aliases:PDJ, AR-JP, parkin, PARK2
Locationchr6:161,347,417-162,727,775
Strand-
Biotypeprotein coding
HGNCHGNC:8607UniProtO60260NCBI Gene5071OMIM602544

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